Nearly 35% of adults in the U.S. aged 65 and over have obesity, and the prevalence of chronic metabolic disease and impaired functional status among older adults with obesity is particularly high.
Older adults with obesity are at particularly high risk of developing cardiometabolic disease such as Type 2 diabetes and cardiovascular disease. Rather than total fat mass, deposition of fat in certain areas, such as the abdominal cavity and skeletal muscle, may confer this greatest risk of disease development.
The study's lead author is Amy Goss, Ph.D., RDN, an assistant professor with University of Alabama at Birmingham's Nutrition Obesity Research Center, Department of Nutrition Sciences. Goss says her team aimed to determine if a low-carbohydrate, high-fat diet would deplete these fat depots and preserve lean mass without intentional caloric restriction in older adults with obesity, thereby improving outcomes related to cardiometabolic disease, such as insulin sensitivity and the lipid profile.